Cu probe

By Targets:	ADC Linker (1) Fluorescent Dye (7)
By Research Areas:	Cancer (1) Neurological Disease (1)
Click Chemistry:	Azide (3) Tetrazine (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D1601

N-Aminofluorescein	Fluorescent Dye	Others
N-Aminofluorescein is a fluorescein hydrazide with spiro form, a highly selective and sensitive fluorescence probe for Cu ²⁺. N-Aminofluorescein has no selective fluorescence response to other common metal ions, can be used for direct detection of Cu ²⁺ in biological systems with λex/em=495/516 nm .

HY-D2288

CalFluor 580 azide	Fluorescent Dye	Others
CalFluor 580 azide is a fluorogenic azide probe that is activated by Cu-catalyzed or metal-free click reaction. CalFluor 580 azide is not fluorescent until it is reacted with alkynes .

HY-D2289

CalFluor 647 azide	Fluorescent Dye	Others
CalFluor 647 azide is a fluorogenic azide probe that is activated by Cu-catalyzed or metal-free click reaction. CalFluor 647 azide is not fluorescent until it is reacted with alkynes .

HY-147104

Fmoc-Lys(5-FITC)-OH	Fluorescent Dye	Others
Fmoc-Lys(5-FITC)-OH is a marker for polypeptides or proteins. FITC is a fluorescence probe for the labeling of amines. FITC is a pH- and Cu ²⁺-sensitive fluorescence dye .

HY-151708

CalFluor 488 Azide	Fluorescent Dye	Others
CalFluor 488 Azide is a water-soluble fluorogenic azide probe. CalFluor 488 Azide is activated by Cu-catalyzed or metal-free click reaction. CalFluor 488 Azide is not fluorescent until it is reacted with alkynes .

HY-141511

Coppersensor 1 1 Publications Verification	Fluorescent Dye	Neurological Disease Cancer
Coppersensor-1 (CS1) is a membrane-permeable fluorescent dye. Coppersensor-1 has a picomolar affinity for Cu ⁺ with high selectivity over competing cellular metalions. Coppersensor-1 as a probe, can selective and sensitive detection of copper(I) ions (Cu ⁺) in biological samples, including live cells. Coppersensor-1 can be used for the research of imaging of severe diseases such as cancer, cardiovascular disorders and neurogenerative diseases .

HY-151691

Trisulfo-Cy3 Methyltetrazine	ADC Linker	Others
Trisulfo-Cy3 Methyltetrazine is a click chemistry reagent containing an methyltetrazine group. Methyltetrazine-activated Cy3 probe reacts with TCO-containing compounds via an Inverse-Electron-Demand Diels-Alder reaction to form a stable covalent bond and does not require Cu-catalyst or elevated temperatures .

HY-150086

Copper Fluor-4 CF4	Fluorescent Dye	Others
Copper Fluor-4 (CF4) is a Cu ⁺-specific fluorescent probe based on a rhodol dye scaffold. Copper Fluor-4 has high copper selectivity, particularly over zinc and iron, as well as abundant cellular alkali and alkaline earth metals. Copper Fluor-4 is stable in a physiologically relevant pH regime between 6 and 8 (Ex: 488 nm) .

Cat. No.	Product Name	Type

HY-D1601

N-Aminofluorescein	Fluorescent Dyes/Probes
N-Aminofluorescein is a fluorescein hydrazide with spiro form, a highly selective and sensitive fluorescence probe for Cu ²⁺. N-Aminofluorescein has no selective fluorescence response to other common metal ions, can be used for direct detection of Cu ²⁺ in biological systems with λex/em=495/516 nm .

HY-141511

Coppersensor 1 1 Publications Verification	Fluorescent Dyes/Probes
Coppersensor-1 (CS1) is a membrane-permeable fluorescent dye. Coppersensor-1 has a picomolar affinity for Cu ⁺ with high selectivity over competing cellular metalions. Coppersensor-1 as a probe, can selective and sensitive detection of copper(I) ions (Cu ⁺) in biological samples, including live cells. Coppersensor-1 can be used for the research of imaging of severe diseases such as cancer, cardiovascular disorders and neurogenerative diseases .

Coppersensor 1

1 Publications Verification

Fluorescent Dyes/Probes

Coppersensor-1 (CS1) is a membrane-permeable fluorescent dye. Coppersensor-1 has a picomolar affinity for Cu ⁺ with high selectivity over competing cellular metalions. Coppersensor-1 as a probe, can selective and sensitive detection of copper(I) ions (Cu ⁺) in biological samples, including live cells. Coppersensor-1 can be used for the research of imaging of severe diseases such as cancer, cardiovascular disorders and neurogenerative diseases .

HY-D2288

CalFluor 580 azide	Fluorescent Dyes/Probes
CalFluor 580 azide is a fluorogenic azide probe that is activated by Cu-catalyzed or metal-free click reaction. CalFluor 580 azide is not fluorescent until it is reacted with alkynes .

HY-D2289

CalFluor 647 azide	Fluorescent Dyes/Probes
CalFluor 647 azide is a fluorogenic azide probe that is activated by Cu-catalyzed or metal-free click reaction. CalFluor 647 azide is not fluorescent until it is reacted with alkynes .

HY-151708

CalFluor 488 Azide	Fluorescent Dyes/Probes
CalFluor 488 Azide is a water-soluble fluorogenic azide probe. CalFluor 488 Azide is activated by Cu-catalyzed or metal-free click reaction. CalFluor 488 Azide is not fluorescent until it is reacted with alkynes .

HY-150086

Copper Fluor-4 CF4	Dyes
Copper Fluor-4 (CF4) is a Cu ⁺-specific fluorescent probe based on a rhodol dye scaffold. Copper Fluor-4 has high copper selectivity, particularly over zinc and iron, as well as abundant cellular alkali and alkaline earth metals. Copper Fluor-4 is stable in a physiologically relevant pH regime between 6 and 8 (Ex: 488 nm) .

Cat. No.	Product Name		Classification

HY-D2288

CalFluor 580 azide		Azide
CalFluor 580 azide is a fluorogenic azide probe that is activated by Cu-catalyzed or metal-free click reaction. CalFluor 580 azide is not fluorescent until it is reacted with alkynes .

HY-D2289

CalFluor 647 azide		Azide
CalFluor 647 azide is a fluorogenic azide probe that is activated by Cu-catalyzed or metal-free click reaction. CalFluor 647 azide is not fluorescent until it is reacted with alkynes .

HY-151708

CalFluor 488 Azide		Azide
CalFluor 488 Azide is a water-soluble fluorogenic azide probe. CalFluor 488 Azide is activated by Cu-catalyzed or metal-free click reaction. CalFluor 488 Azide is not fluorescent until it is reacted with alkynes .

HY-151691

Trisulfo-Cy3 Methyltetrazine		Tetrazine
Trisulfo-Cy3 Methyltetrazine is a click chemistry reagent containing an methyltetrazine group. Methyltetrazine-activated Cy3 probe reacts with TCO-containing compounds via an Inverse-Electron-Demand Diels-Alder reaction to form a stable covalent bond and does not require Cu-catalyst or elevated temperatures .

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
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Inhibitors & Agonists

Fluorescent Dye

Click Chemistry